The Trident School of Biotech Sciences (TSBS) is a unit of TACT(Trust) which has commenced operation w.e.f. the academic session 2002-03. This is a fullfledged college, distinct and different from the MCA/MBA college of TACT. The first course introduced in TSBS was the M.Sc(Biotechnology) course in the session 2002-03, simultaneously with the PG Deptt of Utkal University. Since then, this course has continued with the approval of the State Govt, duly affiliated to the Utkal University, Bhubaneswar.

In 2004, B.Sc (Hons) Biotechnology was introduced in TSBS. The institution is located at the permanent campus of the Trident Group (Trident Technoplex) at F2, Chandaka Industrial Estate, Bhubaneswar-24, right infront of the Infocity of Bhubaneswar, behind Sailashree Vihar.

The School has been attracting students from the entire Eastern India i.e Odisha, West Bengal, Jharkhand, Bihar, Assam and North East and in a recent survey, this has been adjudged as the No.1 Biotechnology college of Eastern India.